Tag: 宁波600品茶

November 18, 2020 | |Post a Comment

first_img Resveratrol is an antioxidant that is found in at least 72 plant species and is known to help protect the heart and nervous system and help prevent cancer, says the report. The researchers did a series of experiments in which they exposed cells to a flu virus and added resveratrol an hour later. They also exposed groups of mice to the virus and treated them with resveratrol or a placebo. The researchers also tested the effects of starting resveratrol treatment at different intervals after infecting cells with the virus. Treatment was most effective—reducing viral growth 87.5%—when treatment began 3 hours after virus exposure. Effects were lower but still significant when treatment began 6 hours after infection, and treatment had no significant benefit if delayed until 9 hours after infection. Rather than directly attacking the flu virus itself, resveratrol seems to block host-cell functions that are essential for viral replication, says the report by Anna T. Palamara and colleagues at the University of Rome. They write that the substance holds promise as a possible weapon against flu. Palamara AT, Nencioni L, Aquilano K, et al. Inhibition of influenza A virus replication by resveratrol. J Infect Dis 2005 May 15;191(10):1719-29 [Abstract] May 31, 2005 (CIDRAP News) – Resveratrol, a chemical found in grapes and other fruits, inhibits the reproduction of influenza viruses in cell culture and mice, according to a recent report in the Journal of Infectious Diseases. “For these reasons, RV merits further investigation as a potential weapon for combating the growing threat of influenza,” the authors conclude. In the tests on mice, the researchers found that resveratrol treatment increased survival by 40% in treated mice, compared with mice that received a placebo. The level of virus found in the lungs 6 days after infection was 98% lower in treated mice than in the placebo group. “We have shown that RV [resveratrol], a natural polyphenol whose concentration in red wine is 1.5-3.0 mg/L, can inhibit the in vitro and in vivo replication of influenza A virus without producing any significant toxicity,” the article states. The apparent ability of resveratrol to block host-cell functions that flu viruses rely on offers important advantages, the researchers say. Compared with existing anti-flu drugs, resveratrol would be less likely to induce resistance by flu viruses, and it would probably be effective for all types and strains of flu virus. In an initial cell-culture experiment, treatment with resveratrol at 20 mcg/mL reduced flu virus replication 90%, and treatment with 40 mcg/mL blocked replication completely. However, because the higher concentration damaged the cells, the lower concentration was used in further tests. Given these and other findings, the researchers concluded that resveratrol interferes with the manufacture of proteins made late in the viral replication process, such as hemagglutinin, and limits the transport of viral ribonucleoproteins from the cell nucleus to the cytoplasm. The authors also determined that the molecular mechanism for resveratrol’s effects has to do with the inhibition of protein kinase C activity and its dependent pathways.last_img read more

August 26, 2020 | |Post a Comment

first_imgHe thrived as a so-called stretch forward last season under Mike D’Antoni’s fast-paced offense that prioritized floor spacing and outside shooting. But Kelly’s role has changed under Byron Scott’s Princeton-based offense. Kelly has primarily played at small forward, including 17 games as a starter. “The four is more of my natural position. In the long term, I think that’s what I’m going to be in the league,” Kelly said. “But the more you can do on the floor, the more valuable you are.” Scott said he changed Kelly’s position in hopes of expanding his game. The Lakers also have plenty of frontcourt options, including Carlos Boozer, Jordan Hill and Ed Davis, that make the power forward position crowded.Yet, Scott said he plans to play Kelly at power forward between five to 10 games at some point in the Lakers’ remaining 25 contests. “He’s guarding guys who are a lot quicker and smaller than him,” Scott said of Kelly. “The more that time goes on, he’s gotten a little bit more comfortable. His natural position is a 4, but I want to experiment with things.”Kelly’s eyes lit up when a reporter informed him Scott plans to play him at power forward. Kelly also conceded he would have altered his offseason workouts last summer had he known he would play at small forward. But Kelly quickly stressed he has embraced the new challenge. “It’s not a bad thing to be playing out of position,” Kelly said. “It gives me a chance to grow.”Injury updateThe Lakers listed Nick Young’s status for Tuesday’s game against Charlotte as questionable because of continued soreness in his left knee. The injury has kept Young sidelined the past three contests. After starring at Duke, where he went 111-15 through four years, Kelly’s two seasons with the Lakers will feature two missed playoff appearances and among the team’s worst records in franchise history.Kelly nursed overlapping hamstring injuries that kept him out for 30 games this season.The Lakers (16-41) also enter Tuesday’s game against the Charlotte Hornets (24-33) at Time Warner Cable Arena with Kelly averaging a 5.1 points on 32.1 percent shooting, a steep drop from when he averaged eight points on 42.3 percent shooting his rookie season.“I still feel very blessed. But it’s obviously frustrating to lose,” Kelly said. “But to be able to play the game I love, I still have the joy to come out and want to work at it.”Kelly has plenty of work. The past year has featured plenty of life-turning events that left Ryan Kelly feeling excited and frustrated. The Lakers signed Kelly this summer to a two-year deal worth around $3.5 million after he showied promise his rookie season as the 48th overall draft pick.Kelly also married his longtime girlfriend, Lindsay Cowher, the daughter of former Pittsburgh Steelers coach Bill Cowher. Yet, Kelly still has stomached some unpleasant experiences. center_img Newsroom GuidelinesNews TipsContact UsReport an Errorlast_img read more